The Digital Library of Alexandria.
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Before we dive into the complicated names, let’s get clear on what we’re talking about. A signaling pathway is like a game of telephone. One molecule passes a message to the next, which passes it to the next, until finally something happens. In the case of TLR4/NF-κB, that "something" is inflammation.
When two neurons fire at the exact same time repeatedly, something physical happens. The synapse between them gets stronger. The "listening" neuron grows more receptors, making it easier to catch the chemical "balls" next time…
To understand Alzheimer’s disease, we must first understand its canvas: the human brain. Hold your hands cupped together. That is roughly the size and weight of the organ that contains everything you are—every memory of your childhood home…
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